rs192543598

This is a downstream gene variant variant.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

severe cutaneous adverse reaction, trait in response to carbamazepine

Nicoletti P et al. Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions. Clinical Pharmacology and Therapeutics 106(5):1028-1036 (2019)
Allele G
OR 18.11
p 2.0e-12
N 10,744
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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rs192543598 — Gene Wizard