rs192570155

This is a 3 prime utr variant variant in the TTC22 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of Sterol ester (27:1/16:0) in blood serum

Tabassum R et al. Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids. Journal of the American Heart Association 11(19):e027103 (2022)
Allele C
OR 0.34
p 5.0e-8
N 4,642
Large GWAS
European

About TTC22

This gene encodes a protein with seven tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]

View all TTC22 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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