rs192746231
This variant is located in the PLD3 gene.
▶ClinVar annotation
About PLD3
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]
View all PLD3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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