rs192804591

This is a intergenic variant variant in the LOC100131289 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

lung cancer, family history of lung cancer

Gabriel AAG et al. “Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden.” Journal of the National Cancer Institute 114(8):1159-1166 (2022)

Allele A

OR 1.14

p 1.0e-11

N 329,946

Large GWAS

European

Barrett's esophagus

Schröder J et al. “GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.” Gut 72(4):612-623 (2023)

Allele A

OR 0.25

p 1.0e-8

N 43,684

Meta-analysisLarge GWAS

European

esophageal adenocarcinoma, Barrett's esophagus

Schröder J et al. “GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.” Gut 72(4):612-623 (2023)

Allele A

OR 0.20

p 3.0e-8

N 49,266

Meta-analysisLarge GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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