rs1971136

This variant is located in the EFR3B gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

breast carcinoma

Michailidou K et al. “Association analysis identifies 65 new breast cancer risk loci.” Nature 551(7678):92-94 (2017)

Allele T

OR 0.04

p 5.0e-9

N 139,274

Large GWAS

multi-ancestry

reaction time measurement

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)

Allele C

OR 0.01

p 5.0e-8

N 404,449

Large GWAS

European

About EFR3B

Involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Located in actin cytoskeleton; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all EFR3B variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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