rs1976748

This is a intron variant variant in the UBE2Q2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

urate measurement

Boocock J et al. “Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.” Human Molecular Genetics 29(6):923-943 (2020)

Allele A

OR 0.04

p 3.0e-12

N 131,709

Large GWAS

multi-ancestry

About UBE2Q2

Enables ubiquitin-protein transferase activity. Involved in protein K48-linked ubiquitination. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all UBE2Q2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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