rs199670311
This is a protein-altering variant in the PGAP6 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
response to opioid, analgesia requirement measurement
Nishizawa D et al. “Genome-wide scan identifies candidate loci related to remifentanil requirements during laparoscopic-assisted colectomy.” Pharmacogenomics 19(2):113-127 (2018)
Allele A
OR 0.13
p 3.0e-8
N 117
Small GWAS
East Asian
About PGAP6
Predicted to enable phospholipase A2 activity. Predicted to be involved in lipid metabolic process. Located in extracellular exosome and lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all PGAP6 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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