rs1999323
This is a intron variant variant in the MAP3K7CL gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
electrocardiography
Verweij N et al. “The Genetic Makeup of the Electrocardiogram.” Cell Systems 11(3):229-238.e5 (2020)
Allele C
OR 0.11
p 6.0e-48
N 63,706
Major Consortium StudyLarge GWAS
European, NR
heart failure
Lee DSM et al. “Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.” Nature Genetics 57(4):829-838 (2025)
Allele T
OR 0.04
p 2.0e-14
N 2,358,556
Large GWAS
multi-ancestry
About MAP3K7CL
Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all MAP3K7CL variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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