rs2000660
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
diastolic blood pressure
Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele A
OR 0.19
p 2.0e-12
N 1,028,980
Large GWAS
multi-ancestry
migraine disorder
Choquet H et al. “New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis.” Communications Biology 4(1):864 (2021)
Allele A
OR 1.06
p 1.0e-10
N 889,018
Meta-analysisLarge GWAS
European
Hautakangas H et al. “Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles.” Nature Genetics 54(2):152-160 (2022)
Allele A
OR 1.05
p 5.0e-8
N 873,341
Large GWAS
European
cardiovascular disease biomarker measurement
Gummesson A et al. “A genome-wide association study of imaging-defined atherosclerosis.” Nature Communications 16(1):2266 (2025)
Allele A
OR 0.22
p 1.0e-9
N 24,811
Large GWAS
European
pulse pressure measurement
Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)
Allele A
OR 0.19
p 1.0e-9
N 1,028,980
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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