rs200300265

This variant is located in the UIMC1 gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About UIMC1

This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

View all UIMC1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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