rs200630980

This variant is located in the TNFRSF10A gene.

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ClinVar annotation

Uncertain Significance★☆☆☆

1 submitter

not specified

About TNFRSF10A

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

View all TNFRSF10A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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