rs201180557
This variant is located in the MECOM gene.
▶ClinVar annotation
Benign★☆☆☆
1 submitter1 publicationAbout MECOM
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
View all MECOM variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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