rs201259422

This is a protein-altering variant in the TSPAN10 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

retinal vasculature measurement

Jensen RA et al. “Novel Genetic Loci Associated With Retinal Microvascular Diameter.” Circulation. Cardiovascular Genetics 9(1):45-54 (2016)

Allele A

OR 0.06

p 4.0e-9

N 24,275

Large GWAS

multi-ancestry

About TSPAN10

Enables enzyme binding activity. Involved in establishment of protein localization to organelle. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

View all TSPAN10 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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