rs201453644
This is a variant in the ACSM3 gene that changes a aspartate to an asparagine.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Hodgkins lymphoma
Osman Y et al. “Functional multigenic variations associated with hodgkin lymphoma.” International Journal of Laboratory Hematology 43(6):1472-1482 (2021)
Allele A
OR —
β 0.036
p 9.0e-11
N 97
Small GWAS
Greater Middle Eastern (Middle Eastern, North African or Persian)
▶ClinVar annotation
Uncertain significance
About ACSM3
Enables medium-chain fatty acid-CoA ligase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Located in mitochondrion. Implicated in IgA glomerulonephritis. Biomarker of ulcerative colitis. [provided by Alliance of Genome Resources, Jul 2025]
View all ACSM3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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