rs202243585

This variant is located in the GRAMD1A gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

complement factor D measurement

Meeks KAC et al. “Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits.” Genome Medicine 13(1):156 (2021)

Allele A

OR 0.28

p 4.0e-8

N 1,510

Large GWAS

multi-ancestry

About GRAMD1A

Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cellular response to cholesterol and intracellular sterol transport. Located in several cellular components, including cytosol; endoplasmic reticulum membrane; and organelle membrane contact site. [provided by Alliance of Genome Resources, Jul 2025]

View all GRAMD1A variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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