rs2032640

This is a intron variant variant in the KDM5D gene.

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Research that mentions this SNP (1)

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Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry
AssociationN=7,810Wang Z. et al.(2012)· Human Genetics

Two-phase association study examining Y chromosome haplogroups and prostate cancer risk in 3,995 cases and 3,815 controls (Stage I) with replication in 1,272 European and 1,686 Ashkenazi Jewish cases. The rare E1b1b1c haplogroup showed nominally significant association with prostate cancer overall (P=0.012, OR=0.51; 95% CI 0.30-0.87) in Stage I, with meta-analysis of stages I and II revealing a nominally significant association with prostate cancer risk (P=0.010, OR=0.77; 95% CI 0.62-0.94).

Traits studied:aggressive prostate cancernon-aggressive prostate cancerprostate cancer
PubMedDOIMetascience Observatory

About KDM5D

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

View all KDM5D variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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