rs2041073
This is a intron variant variant in the HEATR4 gene.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
tetradecadienedioate (C14:2-DC) measurement
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele C
OR 0.47
p 6.0e-145
N 6,136
Large GWAS
European
X-21607 measurement
Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele T
OR 0.27
p 2.0e-142
N 14,296
Large GWAS
European
Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)
Allele T
OR 0.20
p 1.0e-37
N 7,975
Large GWAS
European
X-24748 measurement
Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)
Allele C
OR 0.11
p 9.0e-14
N 8,809
Large GWAS
European
X-13671 measurement
Shin SY et al. “An atlas of genetic influences on human blood metabolites.” Nature Genetics 46(6):543-550 (2014)
Allele T
OR 0.02
p 3.0e-13
N 7,311
Large GWAS
European
2-ketocaprylate measurement
Yin X et al. “Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.” Nature Communications 13(1):1644 (2022)
Allele C
OR 0.13
p 8.0e-13
N 6,136
Large GWAS
European
About HEATR4
Predicted to enable oxidoreductase activity. [provided by Alliance of Genome Resources, Jul 2025]
View all HEATR4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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