rs2041200
This is a regulatory region variant variant in the TBC1D10A gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
urate measurement
Major TJ et al. “A genome-wide association analysis reveals new pathogenic pathways in gout.” Nature Genetics 56(11):2392-2406 (2024)
Allele C
OR 0.02
p 1.0e-12
N 630,117
Large GWAS
European
Cho C et al. “Large-scale cross-ancestry genome-wide meta-analysis of serum urate.” Nature Communications 15(1):3441 (2024)
Allele C
OR 0.02
p 3.0e-9
N 1,029,323
Meta-analysisLarge GWAS
multi-ancestry
About TBC1D10A
Enables PDZ domain binding activity. Involved in positive regulation of proteolysis and retrograde transport, endosome to Golgi. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
View all TBC1D10A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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