rs2051706

This variant is located in the DYNC1I1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

spinal stenosis

Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)

Allele G

OR 0.10

p 4.0e-8

N 633,513

Large GWAS

multi-ancestry

About DYNC1I1

Enables spectrin binding activity. Involved in vesicle transport along microtubule. Located in several cellular components, including kinetochore; recycling endosome; and spindle pole. [provided by Alliance of Genome Resources, Jul 2025]

View all DYNC1I1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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