rs2054576

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

urate measurement

Tin A et al. “Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.” Nature Genetics 51(10):1459-1474 (2019)

Allele A

OR 0.15

p 2.0e-122

N 457,690

Large GWAS

multi-ancestry

4-hydroxychlorothalonil measurement

Hysi PG et al. “Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels.” Metabolites 12(1) (2022)

Allele G

OR 0.48

p 4.0e-83

N 8,809

Large GWAS

European

cyclic adenosine monophosphate measurement

Chen Y et al. “Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.” Nature Genetics 55(1):44-53 (2023)

Allele G

OR 0.19

p 1.0e-10

N 6,756

Large GWAS

European

uric acid measurement

Son CN et al. “ABCG2 Polymorphism Is Associated with Hyperuricemia in a Study of a Community-Based Korean Cohort.” Journal of Korean Medical Science 32(9):1451-1459 (2017)

Allele G

OR 1.88

p 5.0e-8

N 3,647

Large GWAS

East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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