rs2109069

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

COVID-19

Allele A
OR 1.12
p 2.0e-22
N 2,861,299
Large GWAS
multi-ancestry
Allele A
OR 1.26
p 1.0e-21
N 1,489,959
Large GWAS
multi-ancestry
Pairo-Castineira E et al. Genetic mechanisms of critical illness in COVID-19. Nature 591(7848):92-98 (2021)
Allele A
OR 1.20
p 7.0e-13
N 1,170,871
Large GWAS
multi-ancestry

COVID-19, osteoarthritis

Allele A
OR 0.01
p 1.0e-14
N 1,703,231
Large GWAS
European

respiratory failure, COVID-19

Degenhardt F et al. Detailed stratified GWAS analysis for severe COVID-19 in four European populations. Human Molecular Genetics 31(23):3945-3966 (2022)
Allele A
OR 1.17
p 1.0e-19
N 2,641,520
Large GWAS
European, NR

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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