rs2109514

This is a upstream gene variant variant.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

atrial fibrillation

Christophersen IE et al. “Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.” Nature Genetics 49(6):946-952 (2017)

Allele A

OR 1.15

p 7.0e-13

N 111,432

Large GWAS

European

heart rate response to recovery post exercise

Ramírez J et al. “Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system.” Nature Communications 9(1):1947 (2018)

Allele G

OR 0.33

p 7.0e-10

N 67,257

Large GWAS

European

heart rate response to exercise

Verweij N et al. “Genetic study links components of the autonomous nervous system to heart-rate profile during exercise.” Nature Communications 9(1):898 (2018)

Allele G

OR 0.03

p 2.0e-9

N 58,818

Large GWAS

multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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