rs2110942

This variant is located in the STRN gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

hemoglobin A1 measurement

Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele C
OR 0.02
p 6.0e-14
N 415,403
Large GWAS
multi-ancestry

ClinVar annotation

Benign☆☆☆
1 submitter
View on ClinVar →

About STRN

Enables armadillo repeat domain binding activity; nuclear estrogen receptor binding activity; and protein phosphatase 2A binding activity. Involved in Wnt signaling pathway and negative regulation of cell population proliferation. Located in bicellular tight junction. Part of FAR/SIN/STRIPAK complex. [provided by Alliance of Genome Resources, Jul 2025]

View all STRN variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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