rs2137289

This is a intron variant variant in the SKOR2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

age at menarche

Allele A
OR 0.05
p 8.0e-20
N 182,413
Large GWAS
European

About SKOR2

Enables SMAD binding activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all SKOR2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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