rs2195987
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Testicular Germ Cell Tumor
Wang Z et al. “Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor.” Nature Genetics 49(7):1141-1147 (2017)
Allele C
OR 1.23
p 1.0e-9
N 17,528
Meta-analysisLarge GWAS
European
Litchfield K et al. “Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.” Nature Genetics 49(7):1133-1140 (2017)
Allele C
OR 1.22
p 1.0e-8
N 24,573
Large GWAS
European
Kristiansen W et al. “Two new loci and gene sets related to sex determination and cancer progression are associated with susceptibility to testicular germ cell tumor.” Human Molecular Genetics 24(14):4138-46 (2015)
Allele C
OR 1.32
p 3.0e-8
N 8,013
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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