rs2238732
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
proline level, amino acid measurement
Imaizumi A et al. “Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.” European Journal of Human Genetics : Ejhg 27(4):621-630 (2019)
Allele C
OR 0.72
p 1.0e-69
N 1,338
Large GWAS
East Asian
proline level
Imaizumi A et al. “Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.” European Journal of Human Genetics : Ejhg 27(4):621-630 (2019)
Allele C
OR 0.65
p 2.0e-54
N 1,338
Large GWAS
East Asian
Draisma HHM et al. “Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.” Nature Communications 6:7208 (2015)
Allele C
OR 0.18
p 3.0e-39
N 7,475
Large GWAS
European
alanine measurement, amino acid measurement
Imaizumi A et al. “Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.” European Journal of Human Genetics : Ejhg 27(4):621-630 (2019)
Allele C
OR 0.25
p 7.0e-11
N 1,338
Large GWAS
East Asian
valine measurement
Davyson E et al. “Metabolomic Investigation of Major Depressive Disorder Identifies a Potentially Causal Association With Polyunsaturated Fatty Acids.” Biological Psychiatry 94(8):630-639 (2023)
Allele T
OR 0.07
p 4.0e-10
N 88,303
Large GWAS
European
Richardson TG et al. “Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.” Plos Biology 20(2):e3001547 (2022)
Allele T
OR 0.06
p 6.0e-10
N 115,052
Large GWAS
European
body height
Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele T
OR 0.02
p 5.0e-9
N 472,730
Large GWAS
East Asian
saturated fatty acids to total fatty acids percentage
Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)
Allele T
OR —
p 3.0e-8
N 110,346
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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