rs2239347

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Inhalant adrenergic use measurement

Wu Y et al. “Genome-wide association study of medication-use and associated disease in the UK Biobank.” Nature Communications 10(1):1891 (2019)
Allele C
OR 0.07
p 1.0e-13
N 176,445
Major Consortium StudyLarge GWAS
European
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Research that mentions this SNP (1)

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Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut
AssociationN=590Lee KM et al.(2010)· American Journal of Hematology

A case-control study of 108 multiple myeloma cases and 482 controls investigated 870 tag SNPs in 92 immune-related genes. The CD4 gene region (chromosome 12p13-q13) showed the strongest association with multiple myeloma risk (minP=0.0009, FDR=0.07), with rs11064392 (-10912A>G) demonstrating the most significant individual SNP association (OR=2.53, 95% CI=1.59-4.02). Six SNPs across the CD4 and LAG3 genes were significantly associated with multiple myeloma risk.

Traits studied:Multiple myeloma
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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