rs2241606

This variant is located in the SLC12A7 gene.

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ClinVar annotation

Benign★★★☆
2 submitters1 publication
View on ClinVar →
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Research that mentions this SNP (1)

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Genetic Variants in 2q31 and 5p15 Are Associated With Aggressive Benign Prostatic Hyperplasia in a Chinese Population
AssociationN=1,318Jun Qi et al.(2013)· The Prostate

This study evaluated SNPs previously associated with metabolic disorders for associations with prostate volume in 876 men without prostate cancer and 442 men with low-grade prostate cancer, using meta-analysis to combine results. rs11736129 near LOC100131429 was significantly associated with prostate volume (beta: 0.16, p-value: 1.16×10−8), with other SNPs nominally associated including rs9583484 in COL4A2 (beta: -0.11, p-value: 1.01×10−5), rs10146527 in NRXN3 (beta: -0.08, p-value: 3.49×10−5), rs9909466 near RPL32P31 (beta: 0.09, p-value: 5.88×10−5), and rs2241606 in SLC12A7 (beta: 0.07, p-value: 8.51×10−5).

Traits studied:Benign Prostate Enlargement (BPH)Prostate Volume
PubMedDOIMetascience Observatory

About SLC12A7

Enables protein kinase binding activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]

View all SLC12A7 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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