rs2255221

This is a coding sequence variant variant in the HCP5 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

blood protein amount

Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele T
OR 0.57
p 2.0e-45
N 5,353
Large GWAS
European

mean corpuscular hemoglobin

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.04
p 9.0e-44
N 394,642
Large GWAS
European

HIV-1 infection

Pereyra F et al. “The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.” Science (new York, N.y.) 330(6010):1551-7 (2010)
Allele T
OR 2.70
p 4.0e-14
N 3,622
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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