rs2273017
This is a regulatory region variant variant in the TSBP1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Graves disease
Nakabayashi K et al. “Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.” Journal of Human Genetics 56(11):772-8 (2011)
Allele A
OR 1.53
p 2.0e-22
N 3,837
Large GWAS
East Asian
health trait
Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)
Allele G
OR 0.01
p 7.0e-18
N 405,979
Large GWAS
European
About TSBP1
Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all TSBP1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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