rs2274793
This variant is located in the OTX2-AS1 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alcohol consumption quality
Zhou H et al. “Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.” Nature Neuroscience 23(7):809-818 (2020)
Allele T
OR 0.01
p 1.0e-11
N 972,915
Meta-analysisLarge GWAS
European
Cole JB et al. “Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations.” Nature Communications 11(1):1467 (2020)
Allele T
OR 0.01
p 2.0e-9
N 449,210
Major Consortium StudyLarge GWAS
European
Karlsson Linnér R et al. “Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.” Nature Genetics 51(2):245-257 (2019)
Allele T
OR 0.01
p 8.0e-9
N 414,343
Large GWAS
European
alcohol use disorder measurement, alcohol consumption quality
Zhou H et al. “Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.” Nature Neuroscience 23(7):809-818 (2020)
Allele T
OR 0.01
p 8.0e-10
N 972,915
Meta-analysisLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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