rs2276773
This variant is located in the MLF1 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
right ventricular ejection fraction measurement
Aung N et al. “Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function.” Nature Genetics 54(6):783-791 (2022)
Allele A
OR 0.05
p 3.0e-12
N 29,488
Large GWAS
European
right ventricular systolic volume measurement
Aung N et al. “Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function.” Nature Genetics 54(6):783-791 (2022)
Allele A
OR 0.05
p 8.0e-12
N 29,498
Large GWAS
European
right ventricular diastolic volume measurement
Aung N et al. “Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function.” Nature Genetics 54(6):783-791 (2022)
Allele A
OR 0.04
p 5.0e-10
N 29,506
Large GWAS
European
About MLF1
This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
View all MLF1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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