rs2280496
This variant is located in the ADCY1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
IGF-1 measurement, IGFBP-3 measurement
Teumer A et al. “Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits.” Aging Cell 15(5):811-24 (2016)
Allele C
OR —
p 4.0e-12
N 18,995
Meta-analysisLarge GWAS
European
About ADCY1
This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
View all ADCY1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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