rs2292123
This is a downstream gene variant variant in the SLC29A2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
uric acid measurement
Cho SK et al. “Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals.” Scientific Reports 10(1):9179 (2020)
Allele T
OR 0.43
p 1.0e-11
N 6,881
Large GWAS
East Asian
urate measurement
Cho C et al. “Large-scale cross-ancestry genome-wide meta-analysis of serum urate.” Nature Communications 15(1):3441 (2024)
Allele T
OR 0.43
p 1.0e-125
N 1,029,323
Meta-analysisLarge GWAS
multi-ancestry
About SLC29A2
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]
View all SLC29A2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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