rs2301790
This variant is located in the MAN2B2 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein measurement
Western D et al. “Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.” Nature Genetics 56(12):2672-2684 (2024)
Allele G
OR 1.15
p —
N 3,506
Large GWAS
European
epididymis-specific alpha-mannosidase measurement
Allele G
OR 0.33
p 1.0e-44
N 3,301
Large GWAS
European
▶ClinVar annotation
About MAN2B2
Predicted to enable alpha-mannosidase activity. Predicted to be involved in mannose metabolic process and oligosaccharide catabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025]
View all MAN2B2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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