rs2305482

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GWAS Catalog Trait Associations (6)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

interleukin-8 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.06
p 2.0e-30
N 47,745
Large GWAS
European

protein measurement

Folkersen L et al. “Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.” Nature Metabolism 2(10):1135-1148 (2020)
Allele A
OR —
β 0.065
p 6.0e-15
N 21,758
Large GWAS
European

asthma

Zhu Z et al. “Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.” The European Respiratory Journal 54(6) (2019)
Allele A
OR 1.05
p 6.0e-13
N 394,283
Large GWAS
multi-ancestry

neutrophil count

Chen MH et al. “Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.” Cell 182(5):1198-1213.e14 (2020)
Allele A
OR 0.11
p 6.0e-13
N 8,165
Large GWAS
South Asian

level of adhesion G protein-coupled receptor E1 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele C
OR 0.04
p 2.0e-12
N 47,745
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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