rs231770
This is a upstream gene variant variant.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
blood immunoglobulin amount
Wei Y et al. “Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.” Nature Communications 15(1):8004 (2024)
Allele C
OR 0.79
p 9.0e-40
N 69,061
Large GWAS
East Asian
Graves disease
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele T
OR 0.25
p 5.0e-18
N 175,465
Large GWAS
East Asian
Myasthenia gravis
Renton AE et al. “A genome-wide association study of myasthenia gravis.” Jama Neurology 72(4):396-404 (2015)
Allele T
OR 1.39
p 9.0e-11
N 2,949
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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