rs2332719

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

household income

Hill WD et al. “Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.” Nature Communications 10(1):5741 (2019)

Allele G

OR 0.01

p 1.0e-10

N 505,541

Large GWAS

European, NR

intelligence

Schoeler T et al. “Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.” Nature Communications 16(1):4524 (2025)

Allele A

OR 0.02

p 2.0e-10

N 254,641

Large GWAS

European

self reported educational attainment

Schoeler T et al. “Participation bias in the UK Biobank distorts genetic associations and downstream analyses.” Nature Human Behaviour 7(7):1216-1227 (2023)

Allele G

OR 0.03

p 3.0e-10

N 283,749

Major Consortium StudyLarge GWAS

European

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Research that mentions this SNP (1)

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Kalirin: a novel genetic risk factor for ischemic stroke

AssociationN=1,082Tiago Krug et al.(2010)· Human Genetics

Case-control study of 565 Portuguese ischemic stroke patients and 517 controls identifying variants in the KALRN gene region on chromosome 3q13 as risk factors for stroke. Three SNPs showed significant associations: rs4499545 (OR=1.31, P=0.028), rs17286604 (OR=0.70, P=0.010), and rs11712619 (OR=0.74, P=0.030). Genotype imputation identified 32 additional SNPs with P<0.01, with rs11712039 confirmed in a published GWAS. The findings suggest KALRN variants constitute novel genetic risk factors for vascular disease.

Traits studied:Ischemic stroke

PubMed DOI Metascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.