rs2375981
This variant is located in the LOC105375957 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
vascular endothelial growth factor A level
Choi SH et al. “Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.” Plos Genetics 12(2):e1005874 (2016)
Allele C
OR 0.21
p 9.0e-99
N 13,312
Meta-analysisLarge GWAS
European
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.21
p 9.0e-57
N 10,708
Large GWAS
European
Wang Y et al. “Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth.” Plos Genetics 16(11):e1009163 (2020)
Allele C
OR 0.12
p 2.0e-91
N 8,318
Large GWAS
European
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele C
OR 0.23
p 4.0e-33
N 5,364
Large GWAS
European
protein measurement
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.17
p 3.0e-37
N 10,708
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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