rs2378662
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
social inhibition quality, attention deficit hyperactivity disorder, substance abuse
Karlsson Linnér R et al. “Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.” Nature Neuroscience 24(10):1367-1376 (2021)
Allele G
OR 0.01
p 1.0e-16
N 2,776,348
Large GWAS
European
body mass index
Downie CG et al. “Trans-ancestry genome-wide association study of childhood body mass index identifies novel loci and age-specific effects.” Hgg Advances 6(2):100411 (2025)
Allele A
OR 0.03
p 8.0e-9
N 84,840
Large GWAS
multi-ancestry
Hawkes G et al. “Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.” Diabetologia 66(8):1472-1480 (2023)
Allele A
OR 0.01
p 3.0e-8
N 441,761
Large GWAS
European
smoking initiation
Xu K et al. “Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals.” Nature Communications 11(1):5302 (2020)
Allele G
OR 0.98
p 9.0e-9
N 842,717
Meta-analysisLarge GWAS
European
smoking status measurement
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele A
OR 0.02
p 3.0e-9
N 1,232,091
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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