rs240960
This variant is located in the REV3L gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
amygdala volume
Ji Y et al. “Cross-ancestry and sex-stratified genome-wide association analyses of amygdala and subnucleus volumes.” Nature Genetics 57(4):839-850 (2025)
Allele T
OR 0.04
p 4.0e-8
N 35,474
Large GWAS
European
About REV3L
The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]
View all REV3L variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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