rs2416955

This is a intron variant variant in the PPP6C gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of ADP-ribosylation factor-like protein 2-binding protein in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele C

OR 0.07

p 3.0e-15

N 47,745

Large GWAS

European

About PPP6C

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. [provided by RefSeq, Jul 2008]

View all PPP6C variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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