rs2417771

This is a intron variant variant in the PLEKHA5 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

Acute tubulointerstitial nephritis

Zhou XJ et al. Genome-Wide Association Study in Acute Tubulointerstitial Nephritis. Journal of the American Society of Nephrology : Jasn 34(5):895-908 (2023)
Allele A
OR 1.64
p 2.0e-8
N 2,890
Large GWAS
East Asian

About PLEKHA5

Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to act upstream of or within reproductive system development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

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Gene information from NCBI Gene. Variant classifications from ClinVar.

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