rs2424961
This is a regulatory region variant variant in the BPIFB4 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
BPI fold-containing family B member 1 measurement
Allele T
OR —
β 0.440
p 4.0e-71
N 3,301
Large GWAS
European
blood protein amount
Suhre K et al. “A genome-wide association study of mass spectrometry proteomics using a nanoparticle enrichment platform.” Nature Genetics 57(12):2987-2996 (2025)
Allele C
OR 0.26
p 3.0e-13
N 1,193
Large GWAS
multi-ancestry
About BPIFB4
Predicted to enable lipid binding activity. Located in actin cytoskeleton and cytosol. [provided by Alliance of Genome Resources, Jul 2025]
View all BPIFB4 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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