rs2427308
This is a intron variant variant in the CABLES2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
colorectal cancer
Schmit SL et al. “Novel Common Genetic Susceptibility Loci for Colorectal Cancer.” Journal of the National Cancer Institute 111(2):146-157 (2019)
Allele C
OR 1.12
p 2.0e-13
N 67,812
Large GWAS
multi-ancestry
Al-Tassan NA et al. “A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.” Scientific Reports 5:10442 (2015)
Allele C
OR 1.19
p 3.0e-11
N 17,556
Meta-analysisLarge GWAS
European
Whiffin N et al. “Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.” Human Molecular Genetics 23(17):4729-37 (2014)
Allele C
OR 1.24
p 3.0e-11
N 13,443
Meta-analysisLarge GWAS
European
About CABLES2
Predicted to be involved in cell division and regulation of cell cycle. [provided by Alliance of Genome Resources, Jul 2025]
View all CABLES2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…