rs2431108
This is a intron variant variant.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
daytime rest measurement
Dashti HS et al. “Genetic determinants of daytime napping and effects on cardiometabolic health.” Nature Communications 12(1):900 (2021)
Allele C
OR 0.01
p 1.0e-57
N 452,633
Large GWAS
European
insomnia
Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele T
OR 0.01
p 5.0e-29
N 2,365,010
Meta-analysisLarge GWAS
European
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele C
OR 0.01
p 6.0e-17
N 2,669,029
Large GWAS
European
insomnia measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele C
OR 1.05
p 8.0e-17
N 1,331,010
Large GWAS
European
Postural instability
Trajanoska K et al. “Genetic basis of falling risk susceptibility in the UK Biobank Study.” Communications Biology 3(1):543 (2020)
Allele C
OR 1.03
p 4.0e-8
N 451,179
Major Consortium StudyLarge GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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