rs2444770

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GWAS Catalog Trait Associations (5)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

leucine measurement

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 8.0e-14
N 450,015
Large GWAS
multi-ancestry

amino acid measurement

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 7.0e-13
N 450,015
Large GWAS
multi-ancestry

valine measurement

Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 2.0e-11
N 450,015
Large GWAS
multi-ancestry
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Research that mentions this SNP (1)

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Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth
AssociationN=1,935Fasil Tekola-Ayele et al.(2021)· Human Genetics

A genome-wide admixture mapping study of 1,935 pregnant women from diverse ancestral backgrounds identified 10 African ancestry loci and 3 Amerindigenous ancestry loci associated with fetal growth measures. The lead variant rs13030825 (GALNT13) was strongly associated with longer humerus length in African Americans (β=0.44, P=6.25×10⁻⁶ at week 27; β=0.39, P=7.72×10⁻⁵ at week 40), with an FST of 0.55 between African and European populations. The findings identify ancestry-related maternal genetic loci influencing fetal growth across gestation.

Traits studied:Abdominal circumferenceBiparietal diameterBirth weightEstimated fetal weightFemur lengthFetal growth measuresHead circumferenceHumerus length
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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