rs2446297
This variant is located in the FAM13A gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
vital capacity
He Y et al. “Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction.” Nature Genetics 58(2):289-298 (2026)
Allele G
OR 0.02
p 1.0e-15
N 129,680
Large GWAS
East Asian
About FAM13A
Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. Implicated in chronic obstructive pulmonary disease. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM13A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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