rs2450115
This is a intergenic variant variant in the LOC105375712 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
colorectal cancer
Fernandez-Rozadilla C et al. “Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.” Nature Genetics 55(1):89-99 (2023)
Allele C
OR 0.09
p 5.0e-28
N 254,791
Large GWAS
multi-ancestry
Lu Y et al. “Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.” Gastroenterology 156(5):1455-1466 (2019)
Allele C
OR 1.11
p 2.0e-14
N 70,506
Large GWAS
East Asian
Zeng C et al. “Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.” Gastroenterology 150(7):1633-1645 (2016)
Allele C
OR 1.12
p 1.0e-12
N 21,096
Large GWAS
East Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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