rs2480860167
This variant is located in the IRGM gene.
▶ClinVar annotation
About IRGM
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
View all IRGM variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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